摘要
目的：探讨妊娠早、中晚期营养干预对降低巨大儿出生率的影响。方法：随机选择在该院建卡的孕妇分成早孕组、中晚孕组，其中自愿接受早孕期（孕12周内）营养干预的271人为干预组A，中晚孕期（孕24—32周）自愿接受营养干预的207人为干预组B，未接受孕期营养干预的256人为对照组，对干预组进行孕期营养指导、干预和随访，比较干预组和对照组巨大儿出生率等妊娠结局。结果：干预组A巨大儿出生率为5．90％，干预组B巨大儿出生率为8．21％，对照组巨大儿出生率为12．11％，干预组A与对照组之间巨大儿出生率有显著性差异（P〈0．05），干预组B与对照组之间巨大儿出生率无显著性差异（P〉0，05），且干预组A中妊高征、剖官产、胎儿宫内窘迫的发生率明显低于对照组（P〈0．05）；干预组B中剖宫产、产后出血的发生率明显低于对照组（P〈0．05），但胎膜早破的发生率明显高于对照组（P〈0．05），各组间GDM／GIGT的发生率无明显差异。结论：孕早期营养干预可明显降低巨大儿的出生率。
Objective： To study the effects of nutrition interference on the natality of macrosomia of pregnant women in early and intermediate/later period of pregnancy. Methods： Total of 733 pregnant women were selected randomly from the population registered and received management of pregnant period in this hospital and divided into three groups ： Group A （ n = 271 ） and B （ n = 207） were given the interferences from early and intermediate/later pregnant periods respectively through follow - up visits periodieally; Gourp C （n = 256） with no nutrition interference was as eontrol. The pregnancy outcomes of different groups were recorded and analyzed. Results： The natalities of macrosomia in group A, B and C were 6.3%, 8.4% and 12. 0% respectively and there was significant difference between group A and B （ P 〈 0. 05） . Besides, the incidences of pregnancy - induced hypertension syndrome, cesarean delivery rate, intrauterine fetal distress in group A were less than that in group C （ P 〈 0. 05） and the incidences of cesarean delivery rate and postpartum hemorrhage in group B were less than that in group C （ P 〈 0. 05）, but the cases of premature rupture of fetal membranes in group B was high than that in group C （ P 〉 0. 05 ） . However, there were no significant differences on the incidences of GDM/GIGT between these groups. Conclusion： Nutrition interferenee initiating at the early period of pregnancy could obviously reduce the incidence of macrosomia.
出处
《中国妇幼保健》
CAS
北大核心
2007年第32期4567-4569,共3页
Maternal and Child Health Care of China
基金
江苏省南京市医学发展项目资助(N0.YKK0439)
关键词
妊娠期
营养干预
巨大儿
Pregnancy
Nutrition interference
Macrosomia
