摘要
目的:观察比较以祛瘀化痰法组方的眼血散及其拆方防治积血所致增殖性玻璃体视网膜病变的作用及其作用机理。方法:采用玻璃体注血法造成双眼玻璃体积血模型,并随机分成模型对照组、眼血散全方(祛瘀化痰)治疗组、眼血散拆方(祛瘀、化痰)治疗组,观察各组玻璃体积血情况,检测玻璃体中碱性成纤维细胞生长因子(bFGF)、白细胞介素-6(IL-6)的含量。结果:祛瘀化痰(眼血散全方)组及祛瘀组、化痰组(眼血散拆方组)与模型组比较,玻璃体积血明显减轻,bFGF、IL-6含量亦明显降低,尤以眼血散全方组效果显著。结论:眼血散全方及其拆方均能有效清除玻璃体积血,降低玻璃体中bFGF、IL-6的浓度可能是其作用机制之一,全方组比拆方组效果更好。
Objective:To observe and compare the effects and mechanism yanxue powder and its component.Methods:Rabbits' proliferating vitreoretinopathy was induced by hematocele,rabbits were divided into model group,yanxue powder and its components groups,the vitreous hematocele condition was observed,vitreous bFGF and IL-6 were determined.Results:The vitreous hematocele condition was improved in yanxue powder group and its component groups(removing blood stasis group and resolving phlegm group),bFGF and IL-6 contents in vitreous were lower significantly in each Chinese herbs group,the effect of yanxue powder group was the most obvious.Conclusion:Yanxue powder and its components can effectively clear vitreous hematocele,lowering bFGF and IL-6 contents maybe one of its mechanism.
出处
《中国中医药科技》
CAS
2007年第6期398-399,共2页
Chinese Journal of Traditional Medical Science and Technology
