摘要
近年来,吗啡雾化吸入给药作为新的给药途径,因其特殊优点受到临床的关注,通过该途径给药不仅能够产生良好的镇痛作用,还能缓解呼吸困难。本文对吗啡雾化吸入呼吸道给药的药物代谢动力学和药效学以及临床应用的研究进展进行综述。
Nebulized morphine delivery is regarded as a novel method of administration because it can be effec- tively and safely used to control pain, while it relieves dyspnoea without inducing side effects that might be en- countered if given systemically. This review will summarize recent literature on the pharmacokinetics and phar- macodynamics of inhaled morphine as well as the utility in clinic.
出处
《药学与临床研究》
2007年第5期341-343,共3页
Pharmaceutical and Clinical Research
关键词
吗啡
吸入
雾化
药动学
药效学
Morphine
Inhalation
Nebulization
Pharmacokinetics
Pharmacodynamics
