摘要
目的分析含左氧氟沙星方案治疗溃疡型浅表淋巴结结核的效果。方法对117例溃疡型浅表淋巴结结核病人随机分成2组;对照组常规应用异烟肼、利福平、吡嗪酰胺抗结核治疗(2HRZ/4HR);治疗组在常规抗结核治疗的基础上,在强化期加用左氧氟沙星。结果治疗组2个月和4个月的临床治愈率36.1%、73.8%,明显高于对照组16.1%、46.4%(P<0.01),6个月治疗组临床治愈率88.5%,也高于对照组71.1%(P<0.05)。治疗组的平均疮口愈合时间56 d,明显短于对照组79 d(P<0.01)。结论溃疡型浅表淋巴结结核强化期抗结核治疗加用左氧氟沙星,能明显缩短疮口愈合时间,提高临床治愈率,近期疗效显著。
Objective To analyze the therapeatical effect of levofloxacin on superficial lymphous tuberculous ulcer. Methods 117 cases with superficial lymphous tuberculous ulcer were divided into two groups randomly. The control group used routine treatment （2HRZ/4HR）, and the treatment group used levofloxacin（cravit） in addition during the intensive phase. Results The clinical cure rate of the treatment group after two months and four months was 36.1% and 73.8 %, so it was obviously higher than that of the control group of which the rate was 16.1% and 46.4% （P 〈 0.01）. The clinic cure rate of the treatment group at the end of sixth month was 88.5%, which was also higher than that of the control group of which the rate was 71.1% （ P 〈 0.05） .The average cure time of the treatment group was 56 days. It was obviously shorter than that of the control group of which the time was 79 days （P 〈 0.01）. Conclusion Routin anti-tubereulosis drug with levofloxacin in addition to treat superficial lymphous tuberculous ulcer can obviously shorten treatment duration, improve the therapeutically effect and increase the clinic cure rate.
出处
《中国防痨杂志》
CAS
2007年第3期247-249,共3页
Chinese Journal of Antituberculosis
