摘要
目的比较丙泊酚复合芬太尼与丙泊酚复合氯胺酮应用于乳房肿块切除手术的麻醉效果。方法将80例乳房肿块病人随机分为两组,丙泊酚复合芬太尼40例(A组)和丙泊酚复合氯胺酮40例(B组),麻醉后观察两组患者术前、术中SBP、DBP、HR、SpO2的变化,记录用药总量、手术时间、术后意识恢复时间和副作用。结果两组病人年龄、体重和手术时间相比较无显著性差异(P>0.05);B组丙泊酚用量明显少于A组(P<0.05);B组病人生命体征比A组平稳,有显著性差异(P<0.05);苏醒时间B组比A组略长(P<0.05);呼吸抑制B组发生人次比A组少。结论丙泊酚复合氯胺酮应用于乳房肿块切除手术胜于丙泊酚复合芬太尼,具有循环稳定、苏醒迅速和副作用小的优点。
Objective To compare the narcotic effects of propofol combined with fentanyl and with ketamine for breast lumps. Methods Eighty cases with lumps in breast were randomly divided into two groups：40 patients treated with propofol- fentanyl（group A）and the other 40 patients treated with propofol combined ketamine（group B）. After anesthesia,SBP, DBP, HR,SpO2 changes were observed preoperatively and intraoperatively ;the total amounts of drugs, operation time ,postoperative recovery time and awareness, and side effects were recorded respectively. Results The age,weight and operation time of the two groups showed no significant difference （P 〉 0, 05 ） ;the propofol dosage of Group B was less than that of group A （P 〈 0.05 ） ; the vital signs in group B are more stable than that in group A, and showed significant difference（P 〈 0.05 ） ;the recovery time in group B was slightly longer than that in group A（P 〈 0. 05） ;respiratory depression in group B was shorter than that in group A. Conclusions Propofol combined ketamine surgery for breast lumps is more stable, it has shorter recovery time and little side effects.
出处
《医学信息（手术学分册）》
2007年第9期797-798,共2页
Medical Information Operations Sciences Fascicule
