摘要
目的 观察异丙酚和氯胺酮以三种不同浓度配伍在小儿短小手术中的麻醉效果。方法 选择择期短小手术 6 0例 ,随机分为 3组 ,分别以三种不同的配伍方式诱导 :Ⅰ组异丙酚 1mg/kg +氯胺酮 1mg/kg ,Ⅱ组异丙酚1 5mg/kg +氯胺酮 0 6 7mg/kg ,Ⅲ组异丙酚 2mg/kg +氯胺酮 0 34mg/kg ,并按上述比例混合后加盐水至 30ml用注射泵持续注入 ,维持量每组均按异丙酚 5mg/ (kg·h)注入 ,术中出现明显体动时 ,分别静推 1/ 3的诱导量 ,术毕前 5min停药 ,记录诱导给药前、给药后 1min ,给药后 5min ,给药后 15min ,手术结束时的MBP、HR及SPO2 ,术中体动次数 ,术后清醒时间 ,有无噩梦感。结果 三种配伍方式循环均较平稳 ,诱导给药后SPO2均下降 ,但都大于 90 %。Ⅰ、Ⅱ组体动较少 ,Ⅲ组术中体动 (2 3± 0 5 )次 ;苏醒时间Ⅰ组 >Ⅱ组 >Ⅲ组 ;3组术后均无噩梦感。结论 三种配伍方式均可达到满意麻醉效果 ,组Ⅱ配伍更显合理。
Objective To observe the anesthetic effects of disoprofol combined with ketamine in three different concentration for paediatric surgery. Methods Sixty patients were divided into three groups, eath group was induced with diffreat drug combination.Group 1:disopofol 1mg/kg +ketamine 1mg/kg, Group 2:disopofol 1.5mg/kg +ketamine 0.67mg/kg,Group 3:disopofol 2mg/kg +ketamine 0.34mg/kg. Anesthetic state were maintained by micro-pump with diffrent drugs combination. 1/3 of drug dosage were injected when body movement.The MAP,HR, and SPO 2 of patients were recorded when pre-anesthesia, 1min, 5min and 15min after-anesthesia.Times of body movement, awake-time and nightmaive during anesthesia were also recorded.Results Circulation state of patients were stable and SPO 2 decreased in three groups. But figure of SPO 2 were more than 90 pencent.Body movement were 2.3 times in group 3, and it was less in group 1 and group 2,group 1>group 2>group 3 in awake-time.Conclusions Anesthetic effects of three groups were satisfactory,but drug combination in group 2 was more reasonable.
出处
《锦州医学院学报》
2004年第6期14-15,共2页
Journal of Jinzhou Medical College
