摘要
目的通过检测超声乳化白内障吸除联合人工晶状体植入手术前后,葡萄膜炎并发白内障患者房水蛋白浓度,并以老年性白内障患者为对照,了解手术对葡萄膜炎并发白内障患者血-房水屏障的影响,评价术后前房炎性反应的特点。方法对24例(26只眼)葡萄膜炎并发白内障患者及60例(64只眼)老年性白内障患者施行超声乳化联合人工晶状体植入手术,应用激光蛋白细胞检测仪定量检测并比较手术前后的前房蛋白浓度。结果葡萄膜炎并发白内障患者与老年性白内障患者在超声乳化吸除联合折叠式人工晶状体植入术前及术后1、7、30、90 d术眼房水的平均光粒子数分别为(25.12±11.62)、(6.94±0.34);(44.70±11.12)、(26.27±1.37);(31.69±10.12)、(13.96±1.05);(27.59±11.55)、(9.07±0.43)及(23.88±10.43)、(7.16±0.27)photon counts/ms,其中术后1 d、7 d、30 d均高于术前,且差异均有统计学意义(P<0.95);而术后90 d与术前比较,差异无统计学意义(P>0.05)。两组同一时期比较差异均有统计学意义性(P<0.05)。结论超声乳化手术引起葡萄膜炎并发白内障患者血-房水屏障功能的损伤,但在术后短期内可得到重建。超声乳化手术对这类患者是一种安全的、有效的术式。
Objective To evaluate and compare the anterior chamber inflammatory response after phacoemulsification with implantation of foldable intraocular lens（IOL） in patients with uveitis and senile cataract. Methods The aqueous protein concentrations in 26 eyes of 24 patients with uveitis and 64 eyes of 60 senile patients who underwent phacoemulsification with intraocular lens implantation were examined using a laser flare-cell meter. Quantitative measurements of anterior chamber aqueous protein concentration were performed preoperatively and on day 1,7,30 and day 90 after surgery. Results Aqueous flare mean photon counrta in uveitis patients surgery and senile cataract were （25.12 ± 11.62） and （6. 94 ± 0. 34） photon counts/ms before surgery （t=4. 53 ,P 〈0. 05） ;And increased to （44.70± 11.12） and （26. 27 ± 1.37） photon counts/ms on day 1 after surgery （t = 2.30, P 〈 0. 05 ） ; then decreased to （31.69 ± 10. 12） and （ 13.96 ± 1.05 ） photon counts/ms on day 7 after surgery （ t = 2. 36, P 〈 0. 05 ） ; （ 27. 59 ± 11.55 ） and （9.07 ± 0. 43） photon counts/ms on postoperative day 30（t=3.63, P 〈 0.05） ;eventually, the counting decreased to （23. 88 ± 10. 43 ） and （7.16 ± 0. 27 ） photon counts/ms on day 90 after surgery （t = 4. 34, P 〈 0. 05 ） ; Highly statistically significant differences were found between preoperative flare values and those on days 1,7 and 30 after surgery while no statistically significant differences were found between preoperative flare values and those on days 90 after surgery. Conclusion There are disorders of the BAB in cataract patients with uveitis ; The BAB is reestablished in a short time following phacoemulsification with intraocular lens implantation in both groups. Phacoemulsification is a safe and effective method for patients with uveitis.
出处
《中华显微外科杂志》
CSCD
北大核心
2007年第5期348-350,共3页
Chinese Journal of Microsurgery
基金
广东省科技计划项目(30901007)
