摘要
目的:探讨间歇性过量运动对大鼠机体健康的影响及其生物化学机理。方法:45只Wistar大鼠随机分为3组(每组15只):安静对照组(C)、一般运动组(NE,在动物跑台15m.min-1运动,每周运动5d,每天运动时间30min×2,间歇10min)和过量运动组(OE,每周连续2天进行2次过量运动,速度为20m.min-1,每次运动时间100min×2,间歇10min)。3组大鼠运动8周后处死,对大鼠血液中血红蛋白、红细胞压积等15项生化指标进行检测。结果:与C组和NE组比较,OE组大鼠血液中磷酸肌酸激酶(CK)、乳酸脱氢酶(LDH)、丙氨酸转氨酶(ALT)明显升高(P<0.05或P<0.01),血红蛋白(HGB)、IgG、总蛋白(TP)、白蛋白(ALB)明显降低(P<0.05或P<0.01)。与C组比较NE组WBC、RBC、HDL、TP、IgG明显升高(P<0.05或P<0.01),LDL明显降低(P<0.01)。结论:间歇性过量运动对大鼠血液中的某些生化指标产生不良的影响。
Objective To study the influence of interim overload exercise on health and it＇s biochemical mechanism. Methods 45 Wistar rats were randomly divided to three groups （n=15） ： no exercises group （control, C）, normal exercise group （NE , the rats ran in the animal running machines at 15 m · min^-1 for 5 d in one week , exercise time was 30 min×2, and rested for 10 min after ran for 30 min） , overload exercise group （OE, the rats exercised 2 bouts, 2 d in consecutive in one week, exercise time was 100 min×2, and they rested for 10 min after ran for 100 min ）. After training for 8 weeks , the rats in three groups were sacrificed and 15 biochemical indexes in blood of rats were determined . Results Compared with C and NE groups , CK , LDH , and ALT increased obviously （P〈0.05 or P〈0.01 ） ; HGB , IgG , TB and ALB decreased （P〈0.05 or P〈0.01 ） in OE group; compared with C group, WBC , RBC , HDL , TP and IgG increased obviously （P〈0.05 or P〈0.01 ）, and LDL decreased （ P〈0.01 ） in NE group. Conclusion Interim overload exercise has some bad influence on biochemical indexes in blood of rats.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2007年第5期875-878,共4页
Journal of Jilin University：Medicine Edition
基金
吉林省科技厅科技发展计划项目资助课题(20000200)
