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A new isochroman-4-one derivative from the peel of Musa sapientum L.and its total synthesis 被引量：4

A new isochroman-4-one derivative from the peel of Musa sapientum L.and its total synthesis
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摘要 A new isochroman-4-one, 7,8-dihydroxy-3-methylisochroman-4-one was isolated from water soluble fraction of Musa sapientum L. Its structure was determined by spectroscopic evidences and its total synthesis has also been reported. The compound showed potent antihypertensive activity. A new isochroman-4-one, 7,8-dihydroxy-3-methylisochroman-4-one was isolated from water soluble fraction of Musa sapientum L. Its structure was determined by spectroscopic evidences and its total synthesis has also been reported. The compound showed potent antihypertensive activity.
作者 Hai Qian Wen Long Huang Xiao Ming Wu Hui Bin Zhang Jin Pei Zhou Wen Cai Ye
机构地区 Center of Drug Discovery Department of Medicinal Chemistry Department of Phytochemistry
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2007年第10期1227-1230,共4页 中国化学快报（英文版）
关键词 Isochroman-4-one Musa sapientum L. ISOLATION Total synthesis Isochroman-4-one Musa sapientum L. Isolation Total synthesis
分类号 TQ461 [化学工程—制药化工]
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参考文献11

  • 1[1]Z.D,Cidian,Grand Dictionary of Chinese Traditional Medicine,in Chinese,2nd ed.,Shanghai Science and Technology Press,Shanghai,2005,p.178. 被引量：1
  • 2[2]D.A.Lewis,G.P.Shaw,J.Nat Biochem.12 (2) (2001) 95. 被引量：1
  • 3[3]A.Hihiro,K.Yumiko,T.Toshitake,Phytochemistry 47 (6) (1998) 1107. 被引量：1
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  • 8[8]The peels of M.sapientum L.were collected in Guangxi province in September 2004.The plants were identified by Professor Li Ping,the Department of Pharmacognosy,China Pharmaceutical University.A voucher specimen (QH20040918) was deposited in the laboratory of the School of Pharmacy,China Pharmaceutical University. 被引量：1
  • 9[9]A.B.Bueno,W.H.Moser,L.S.Hegedus,J.Org.Chem.63 (5) (1998) 1462. 被引量：1
  • 10[10]Spectral data:compound 5:IR (KBr):3459,3087,2982,2938,2836,1742,1588,1483 and 1278 cm-1; MS (ESI,m/z):[M-H]-239; 1H NMR (300 MHz,CDCl3,δppm):1.50 (d,3H,J= 6.9 Hz),3.89 (s,3H),3.93 (s,3H),4.12 (q,1H,,J= 6.9 Hz),4.56 (d,1H,J=10.5 Hz),4.64 (d,1H,,J= 10.5 Hz),6.93-7.09 (m,3H). 被引量：1

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Chinese Chemical Letters
2007年 第10期

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