摘要
目的：建立妇科千金胶囊中穿心莲内酯和脱水穿心莲内酯的含量测定方法。方法：以XTerra RP18色谱柱为分离柱,以甲醇-水（45∶55）为流动相,采用HPLC法测定。结果：本品中穿心莲内酯含量测定线性范围为（16～160）μg·mL-1（r=0.999 9）,平均回收率为98.4%（RSD=3.8%,n=5）;脱水穿心莲内酯含量测定线性范围为（8～80）μg·mL^-1（r=0.999 9）,平均回收率为98.7%（RSD=3.7%,n=5）。结论：此法操作简单、结果准确,可用于妇科千金胶囊的质量控制。
Objective. To establish a method for the determination of Andrographolide and Dehyandrographolide in Fukeqianjin Capsules. Methods：Using the method of HPLC, the XTerra RP18 radial compression column was used with a mobile phase of methanol-water（45 ： 55）. Results： The linear range of andrographolide was （16- 160）μg·mL^-1（ r = 0.999 9）, and the average recovery was 98.4 % （ RSD = 3.8%, n = 5 ） ; the dehydroandrographolide was （8 - 80） μg·mL^-1 （ r =0. 999 9）, and the average recovery was 98.7 % （ RSD = 3.7 %, n = 5 ）. Conclusion： This method was simple and feasible for the quality control of Fukeqianjin Capsules.
出处
《中国实验方剂学杂志》
CAS
2007年第10期4-6,共3页
Chinese Journal of Experimental Traditional Medical Formulae
