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聚吡咯/聚乳酸电活性复合物的制备与表征 被引量:1

Preparation and Characterization of Polypyrrole/polylactic acid Electric Active Composite
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摘要 制备聚吡咯/聚乳酸(PPy/PLA)电活性复合膜并对其表征。应用乳液聚合法制备PPy/PLA复合膜,通过扫描电镜、红外光谱检测复合膜的表面特征和结构特点,使用直流电刺激系统测定复合膜的导电稳定性。结果表明:扫描电镜观察PPy颗粒连续分散在PLA基质中,红外光谱检测显示有PPy和PLA的吸收峰,直流电刺激系统测定复合膜电导率缓慢下降,在560h到1146h之间电流持续保持在28~35μA。表明制备的PPy/PLA电活性复合膜确实含有PPy和PLA高分子聚合物,40天内在生理环境条件下仍具有生物意义的直流电。这种结合导电性和生物相容性的材料将在组织工程中有着广泛的应用。 To prepare and characterize the PPy/PLA electro-active composite. PPy/PLA electro-active composite was prepared with the emulsion polymerization method and measured by SEM and FT-IR, Then conductive stability was determined with DC electric stimulation system, Result showed that PPy particle dispersed continuously into PLA substance by SEM. Absorbing apex of PLA and PPy could be seen in FT-IR spectra, Electric conductivity decreased slowly and sustained at 28 - 35 μA from 560h to 1146h,It is concluded that PPy/PLA electro-active composite possess biosignificant DC electric current and has potential useful in tissue engineering.
出处 《生物医学工程研究》 2007年第3期275-277,共3页 Journal Of Biomedical Engineering Research
基金 国家自然科学基金资助项目(10572017 10632010)。
关键词 聚吡咯/聚乳酸电活性复合膜 制备 表征 表面特征 导电稳定性 Polypyrrole/polylactic acid Preparation Characterization Surface character conductive stability
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  • 1段宏,樊瑜波,陈坚,裴福兴,沈彬.外源性碱性成纤维细胞生长因子促膜引导性骨再生的实验研究[J].生物医学工程学杂志,2004,21(6):879-883. 被引量:4
  • 2贺进田,陶贤梅,莫炜,宋后燕.葡激酶突变体(K35R)PLGA微球的制备和表征(英文)[J].药学学报,2006,41(1):12-18. 被引量:13
  • 3姜文学,曹现林,徐东明,胡茂忠,尤佳,孙洪范.诱导性人工骨膜复合异体骨移植修复兔桡骨缺损[J].中华骨科杂志,2006,26(5):336-341. 被引量:10
  • 4Morita T,Horikiri Y,Suzuki T,et al.Applicability of various amphiphilic polymers to the modification of protein release kinetics from biodegradable reservoir-type microspheres[J].Eur J Pharm Biopharm,2001,51:45-53. 被引量:1
  • 5Kwon YM,Kim SW.Biodegradable triblock copolymer microspheres based on thermosensitive sol-gel transition[J].Pharm Res 2004,21:339-343. 被引量:1
  • 6Persad R.Leuprorelin acetate in prostate cancer:a European update[J].Int J Clin Pract,2002,56:389-396. 被引量:1
  • 7Cook DM,Biller BMK,Vance ML,et al.The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (Nutropin Depot) in GH-deficient adults[J].J Clin Endocrinol Metab,2002,87:4508-4514. 被引量:1
  • 8Zhang JX,Zhu KJ,Chen D.Preparation of bovine serum albumin loaded poly (D,L-lactic-co-glycolic acid) microspheres by a modified phase separation technique[J].J Microencapsul,2005,22:117-126. 被引量:1
  • 9Burke PA,Klumb LA,Herberger JD,et al.Poly(lactide-co-glycolide) microsphere formulations of darbepoetin alfa:spray drying is an alternative to encapsulation by spray-freeze drying[J].Pharm Res,2004,21:500-506. 被引量:1
  • 10Giunchedi P,Conti B,Genta I,et al.Emulsion spray-drying for the preparation of albumin-loaded PLGA microspheres[J].Drug Dev Ind Pharm,2001,27:745-750. 被引量:1

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