摘要
目的探讨羌银解热汤对小鼠感染甲1型流感病毒FM1株的抑制作用及对小鼠的死亡保护作用。方法利用甲1型流感病毒FM1株感染小鼠为动物模型,以肺指数与肺指数抑制率和死亡率为评价指标,观察羌银解热汤大、中、小剂量组在小鼠体内的抗流感病毒作用。结果羌银解热汤大、中剂量组可以有效抑制病毒引起的小鼠肺部病变、降低肺指数;羌银解热汤大剂量组与病毒对照组相比,死亡保护率有显著性差异。结论羌银解热汤具有良好的体内抗流感病毒感染作用;能降低甲1型流感病毒感染小鼠的死亡率,对流感病毒感染小鼠有死亡保护作用。
Objective： To observe the protective effects of Qiangyinjieretang on th mice infected with influenza A virus FM1 strain. Methods： the impacts on lung index ang death reate of mice infected with influenza virus were observed in the mice infected with virus. Results： Qiangyinjieretang at the concentrations of 4g/100g and 2g/ 100g for the treatment markedly inhibited the lung consolidation of mice pneumonia caused by the infection of influenza virus. Compared with the model group, the death rate of mice of Qiangyinjieretang at the concentrations of 4g/100g was lower. Conclusion： Qiangyinjieretang is markedly effective for treatment of ifeetion with influenza virus.
出处
《中国中医急症》
2007年第9期1105-1106,共2页
Journal of Emergency in Traditional Chinese Medicine
基金
广东省中医药局资助课题(No.105182)
中山市科技局立项课题(No.2005A078)
关键词
流感病毒
羌银解热汤
实验研究
Influenza A virus
Qiangyinjieretang
Experimental study
