摘要
目的通过对符合药典规定的金银花中绿原酸的转移率进行考察,建立药材的有效成分转移率检查项,达到控制成品的目的,同时对现行的金银花药材质量标准进行完善,建立金银花的内控质量标准。方法采用同一提取方法对不同批次金银花药材中的绿原酸提取转移率进行考察,对结果进行分析。结果不同批次金银花药材在符合药典规定和内控指纹图谱规定的基础上,按照相同工艺进行提取,绿原酸提取转移率相差较大。即符合药典规定和内控指纹图谱规定的金银花药材,可能会因为其提取转移率不合格,而导致成品不合格。结论建议在金银花药材标准中加入"有效成份转移率"检查项以更好地控制药材内在质量,从而保障使用金银花原药材的中成药的质量。
OBJECTIVE To establish examination methods for detecting effective components of medicinal materials by observing the transfer rate of ehlorgenic acid in Flos Lonicerae Japonicae; to perfect the available quality standards of Flos Lonicerae Japonicae so as to establish the internal control quality standards of Flos Lonicerae Japonicae. METHOD Observations were made on the transfer rate of chlorgenie acid in different batches of Flos Lonicerae Japonicae, using the same extraction method, followed by an analysis of the results. RESULT Different batches of the medicinal herb showed different transfer rate although the extraction method was the same, which is likely to cause failure to meet the quality standards. CONCLUSION The authors suggest that it is advisable to add the examination item ＂transfer rate of effective component＂, so as to better control the quality of the medicinal materials and ensure the quality of the patent Chinese medicine with Flos Lonicerae Japonicae as one of the ingredients.
出处
《南京中医药大学学报》
CAS
CSCD
2008年第5期350-352,共3页
Journal of Nanjing University of Traditional Chinese Medicine
基金
江苏省科技成果转化基金项目(BZ2004031)
关键词
转移率
金银花
绿原酸
transfer rate
Flos Lonicerae Japonicae
chlorgenic acid
