摘要
目的评价通过血清心肌肌钙蛋白I(cTnI)时间-浓度曲线计算的心肌梗死体积(MIS)在急性心肌梗死中的价值。方法选择2002年9月至2003年9月的31例急性ST段抬高型心肌梗死(ASTEMI)患者为研究对象。采用酶联免疫分析法检测血清cTnI水平3次以上,利用血清cTnI的时间-浓度曲线估测MIS。运用统计学方法分析MIS与肌酸磷酸激酶(CK)同工酶MB(CK-MB)峰值、LVEF的关系。结果(1)MIS与CK-MB峰值具相关性,r值为0.73(P<0.05)。(2)MIS≥40cTnI-g组LVEF值明显小于MIS<40 cTnI-g组(P<0.05)。结论(1)cTnI具有很高的心肌特异性,可用于AMI的诊断和排除诊断。(2)利用cTnI估测出ASTEMI患者的MIS,MIS与CK-MB峰值密切相关。(3)MIS与ASTEMI患者的心功能相关。
Objective To evaluate the myocardial infarct size （MIS）gained by serum time-consistency curve of cardiac troponin Ⅰ （cTnI） for acute ST-segment elevated myocardial infarction （ASTEMI）. Methods Thirty-one patients undergoing ASTEMI were observed. The serum cTnI level was measured for at least 3 times and calculated MIS using serum time-consistency curve of cTnI. The relationships between the MIS and peak CK-MB level and LVEF was evaluated by statistical analysis. Results （1） The correlation was observed between infarct size and peak serum CK-MB level（r=0. 73,P〈0. 05）. （2）The LVEF in MIS≥40cTnI-g group was lower than MIS〈40cTnI-g group（P〈0.05）. Conclusion （1）Serum cTnI levels have high specificity for myocardium. It can be used for roll in and roll out AMI patients. （2） We can gain infarct size accurencely by series serum cTnI levels. （3）Infarct size is statistically correlated with peak CK-MB level and LVEF.
出处
《江西医学院学报》
2007年第4期23-25,共3页
Acta Academiae Medicinae Jiangxi
