摘要
目的探讨2型糖尿病(T2DM)患者发生外周血管病变(PVD)的危险因素。方法选取180例T2型DM患者,其中合并PVD80例,无PVD100例,检测相关临床指标。结果T2DM合并PVD组糖尿病病程、血清肌酐、总胆固醇、高密度脂蛋白胆固醇、高血压、脑梗死史、高敏C反应蛋白(hsC-RP)和白细胞介素6(IL-6)水平显著高于无PVD组。多因素回归分析显示hsC-RP和糖尿病病程与T2DM并发PVD正相关。结论hsC-RP是促使T2DM并发PVD的独立危险因素。
Objective To study the risk factors for peripheral vascular disease（PVD） in subjects with type 2 diabetes mellitus.Methods Related risk factors were analyzed in 80 type 2 diabetic patients with peripheral vascular disease and in 100 type 2 diabetic patients without peripheral vascular disease.Results Type 2 diabetes patients with PVD had longer diabetic duration,higher serum creatinine level,higher TC/HDL-C,higher serum levels of hsC-RP and IL-6 and more freguent histories of hypertension and cerebral infarction than did those without PVD.Multivariate regression analysis showed higher serum level of C-RP and longer diabetic duration were independent risk factors for PVD in type 2 diabetes mellitus.Conclusions C-RP and diabetic duration are independent risk factors for PVD in type 2 diabetes.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2007年第8期483-484,共2页
Chinese Journal of Diabetes
关键词
糖尿病
2型
外周血管病变
危险因素
Diabetes mellitus,type 2
Peripheral vascular disease
Risk factors
