摘要
目的:评估多层螺旋CT仿真内镜(MSCTVE)在鼻咽癌诊断中的价值。材料及方法:24例研究对象进行多层CT扫描(其中22例经病理证实的鼻咽癌,2例鼻咽腔正常研究对象)同时进行纤维内镜对照检查。2名影像医师进行鼻咽部多层螺旋CT仿真内镜漫游,仿真内镜所见与纤维内镜结果用四分法和六分法进行对照评估。结果:MSCTVE能够很好的显示鼻咽腔解剖和鼻咽癌所致鼻咽腔异常(P<0.01),然而不能对黏膜结构病理变化或异常的成因变化做出正确分析(P<0.05),MSCTVE和纤维内镜有很好的相关性。结论:MSCTVE是一种能够很好的显示解剖或病变的表面细节的新影像技术。尽管MSCTVE存在着不能分析黏膜结构病理变化或异常的成因,同时也不能进行组织活检诊断,但是MSCTVE作为一种无创的技术在鼻咽癌诊断和临床实践中发挥着重要的作用。
Objective: In the present study, multi-slice computed tomography virtual endoscopy(MSCTVE) was evaluated in the diagnosis of nasopharyngeal carcinoma. Methods: Twenty-four patients with nasopharyngeal carcinoma and normal nasophrynx confirmed by pathology underwent multi-slice CT scanning performed with GE Prospeed16 and flexible endoscopy(FE). Two radiologists using Fly Through software generated both antegrade and retrograde endoluminal virtual endoscopy navigation of the nasopharynx. The results of the radiological study were compared with flexible endoscopic findings using six-point and four-point rating scale. Results: MSCTVE appeared to be more accurate in visualization and evaluation of nasopharyngeal anatomy and abnormalities caused by nasopharyngeal carcinoma (P〈0.01), however depictions of mucosal surface were difficult or inaccurate(P〉0.05). There was good overall correlation between virtual images and flexible endoscopic findings. Conclusion: MSCTVE is a new radiographic technique that can depict clearly the anatomy and morphological changes in nasopharyngeal carcinoma. This technique is undergoing rapid growing, however there are some limitations such as characterization of lesion and inability to obtain biopsy. We are of the opinion that MSCTVE is a non-invasive and useful technique for nasopharyngeal carcinoma in diagnoses and clinical practice.
出处
《中国临床医学影像杂志》
CAS
北大核心
2007年第8期563-565,共3页
Journal of China Clinic Medical Imaging
关键词
鼻咽肿瘤
体层摄影术
X线计算机
nasopharyngeal neoplasms
tomography, X-ray computed