摘要
目的:探讨维持性血液透析(MHD)患者标志物对血管疾病预测价值。方法:维持性血液透析患者49例,心血管疾病非维持性血液透析组23例(C组),正常对照30例。血液透析患者分心血管疾病组17例(A组)和非心血管疾病组32例(B组),检测血TG、TC、HDL-C、LDL-C、Fg、D-D、vWF、CRP。结果:心血管疾病组患者的年龄明显高于无心血管疾病组(P<0.01);A组患者TG、TC、HDL-C、LDL-C、Fg、D-D、vWF、CRP增高,与正常对照组及B组、C组相比差异具有显著统计学意义(P<0.05)。多元Logistic逐步回归分析证实:Fg、D-D、vWF、CRP是心血管疾病的致病危险因素。结论:MHD患者发生心血管并发症与Fg、D-D、vWF、CRP有一定的关系。
Objective：To investigate the prognostic values of blood markers on mortality and cardiovascular events in maintenance hemodialysis （MHD） patients.Methods：49 MHD patients, 23 cardiovascular disease（CVD） without MHD patients and 30 healthy volunteers were enrolled in this study.MHD patients including 17 MHD patents with CVD and 32 MHD patents with non-evident cardiovascular disease history. Serum CRP,Lp（a）,TG, TC, HDL-C,LDL-C,ALB,plasma Fg,D-D and vWF were measured.Results： Both homodialysis patients with and without prevalent CVD had significantly higher levels of all these parameters compared with controls （P〈 0.05）0 Four risk factors were confirmed by means of the Logistic regression analysis：Fg,D-D,vWF,CRP. Conclusion：Fg,D-D,vWF,CRP are associated with the mortal cardiovascular events maintenance HD patients.
出处
《泸州医学院学报》
2007年第4期273-275,共3页
Journal of Luzhou Medical College
