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肿瘤细胞耐受光动力疗法分子机制的研究进展 被引量:1

Advances in the study of molecular mechanism of tolerance of tumor cells to photodynamic therapy
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摘要 光动力疗法(PDT)可诱导肿瘤细胞凋亡,治疗消化道肿瘤,或对无法手术的癌症晚期患者进行姑息治疗。因PDT致肿瘤细胞的凋亡率并未达100%,肿瘤细胞耐受PDT的原因目前还不明了,据相关文献报道可能与血红素加氧酶-1、热休克蛋白、锰超氧化物歧化酶、Bcl-2蛋白家族等许多因素相关。现就已知的造成肿瘤细胞耐受光动力疗法的各种分子机制作一简要综述。
出处 《中国普通外科杂志》 CAS CSCD 2007年第7期684-686,共3页 China Journal of General Surgery
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