摘要
目的分析脑卒中后抑郁(post-stroke depression,PSD)的发病相关因素。方法对入选的237例脑卒中患者的性别、年龄、文化程度、行为类型、卒中类型、脑卒中病灶部位、神经功能缺损程度评分、社会支持度评分、汉密尔顿抑郁量表评分进行记录。单因素分析t检验和χ2检验;多因素分析进行非条件Logistic回归分析。结果单因素分析表明:文化程度、卒中类型与PSD的发生无关(P>0.05)。而行为类型A型行为PSD组77例,非PSD组25例,神经功能损伤程度PSD组(28.91±7.56)分,非PSD组(20.10±7.78)分,脑卒中病灶部位左前、左后、右前、右后PSD组为64例、20例、14例、14例;非PSD组25例、36例、30例和34例,社会支持程度PSD组(33.40±3.84)分,非PSD组(42.89±3.91)分,与PSD的发生有关(均P<0.01)。多因素Logistic分析显示:A型行为类型者发生PSD的可能性为非A型者的8.642倍;神经功能缺损程度与PSD的发生呈正相关;社会支持程度与PSD发生呈负相关;损伤部位位于左前半球时,最易患PSD。结论PSD的发病与多种因素有关。
Objective To analyze the connecting pathogenetic factors in post-stroke depression（PSD）. Methods Two hundred thirty-seven apoplexy patients were recorded about their gender, age, literacy, style of behavior, the character of stroke,the parts of apoplexy focus degrees of nervous function deficiency, social support, the marking of Hamilton depressive scale. Single-factor analysis was checked with t and Xz test, and then multi-factor analysis was carried on the logistic regression analysis. Results The regression analysis of the single factor showed：the occurrence of PSD had no connection with literacy and stroke character （ P 〉0.05）. However,the type of behavior PSD group had 77 cases of type A patients, non-PSD group had 25 cases, the degree of nervous function deficiency, PSD group was （28.91 ± 7.56） points, non-PSD group was （20.10 ± 7.78） points, focus part, the focus located in left front hemisphere, left rear ward hemisphere, right front hemisphere, right rear ward hemisphere PSD group respectively were 64 cases, 20 cases, 14 cases, 14 cases; non-PSD group was 25 cases, 36 cases 30, cases and 34 cases, the degree of social support,PSD group was （33.4 ± 3.84） points, non-PSD group was （42.89 ± 3.81） points, had connection with PSD occurrence（all P 〈0.01）. The analysis of multiple factors showed：the possible of PSD occurrence on type A was 8. 642 times higher than that happened on non type A; the degree of nervous function deficiency positively correlated with the occurrence of PSD, the social support negatively correlated with PSD. If the injury happened in the left front hemisphere,the patients were easy to get PSD. Conclusion The occurrence of PSD had much to do with multiple factors.
出处
《临床荟萃》
CAS
北大核心
2007年第15期1074-1076,共3页
Clinical Focus
关键词
脑血管意外
抑郁
体层摄影术
X线计算机
cerebrovascular accident
depression
tomography, X-ray computed
