摘要
地方性砷中毒对人体造成的远期致癌效应,一直是世界各国广泛关注的问题。本文就砷的致癌机制研究中的一些热点问题,从遗传学机制和拟遗传学机制两个方面进行了综述,对砷影响免疫分子和细胞缝隙连接间通讯作用的有关研究进行了总结,并提出了今后研究工作的一些设想。
The long - term effects induced by endemic arsenic poisoning disease attract wide attention worldwide. Based on public survey on the mechanism of carcinogenesis induced by arsenic, this article introduces recent studies on two aspects- genetic mechanism and epigenetic mechanism, and also summarize the effects on immune molecules and the functions of gap junctional intercellular communication. The author also brings forward some considerations on further studies of the carcinogenesis research.
出处
《中国地方病防治》
北大核心
2007年第4期264-267,共4页
Chinese Journal of Control of Endemic Diseases
关键词
地方性砷中毒
致癌性
研究
Endemic arsenic poisoning disease
Carcinogenesis
