摘要
目的比较米氮平和氯米帕明治疗老年抑郁症的疗效和不良反应.方法将78例老年抑郁症患者随机分为米氮平组与氯米帕明组,疗程8周。采用汉密尔顿抑郁量表(HAMD)评定疗效,用副反应量表(TESS)评定不良反应.结果米氮平组与氯米帕明组的有效率分别为82%和76.9%,二者疗效相仿。结论米氮平是一种安全、有效的抗抑郁药物,能用于老年抑郁症患者。
Objective To compare the efficacy and safety of mirtazapine and chlorimipramine in the treatment of elderly depressive patients. Methods Seventy-eight elderly patients with depression were randomly divided into mirtazapine group and chlorimipramine group for 8 weeks respectively. The efficacy and side effects were evaluated by Hamilton depressive Scale （HAMD） and treatment emergent sympton scale（TESS）. Results The effective rates of mirtazapine and chlorimipramine were 82% and 76. 9 % respectively, which was no significant difference betweem two groups. Conclusion Mirtazapine is a safe and effective drug in the treatment of geriatric depression.
出处
《中国健康心理学杂志》
2007年第8期673-674,共2页
China Journal of Health Psychology
