摘要
目的观察安神补脑液对小鼠学习记忆能力及脑内蛋白质合成的影响。方法用Y-型水迷宫法、跳台法测定小鼠的学习记忆能力,Lowry法测定小鼠脑内蛋白质,二苯胺试剂显色法测定DNA,Oricinol试剂显色法测定RNA的含量。结果安神补脑液对正常小鼠的记忆能力有增强作用,对乙醇致小鼠记忆再现障碍有改善作用,并能显著增加小鼠脑内蛋白质、DNA的含量。结论安神补脑液能提高正常及记忆再现障碍小鼠的学习记忆能力,其作用机制可能与其促进脑内蛋白质合成有关。
Objective To observe the effect of Anshenbunao Syrup on learning and memory capability in mice. Methods The learning and memory capability of mice was investigated by Y-water maze test and step-down test. The contents of protein, DNA and RNA were investigated by Lowry methods, the diphenylamine reagent method and Oricinol reagent method. Result Anshenbunao Syrup could enhance the memory capability of normal mice and improve the memory emersion disorder of mice induced by ethanol. In addition, it could increase the contents of protein and DNA in brain of mice. Conclusion Anshenbunao Syrup could improve the Iearning and memory capability of normal and memory emersion disorder mice, and its mechanism may be related to promoting protein synthesis in brain.
出处
《中国中医药信息杂志》
CAS
CSCD
2007年第8期30-31,共2页
Chinese Journal of Information on Traditional Chinese Medicine
