摘要
目的对子宫颈癌和癌前病变的检查方法进行综合分析比较与评价,以期找到宫颈癌早期筛查的最佳方案。方法2006年1—8月,对1 061例患者分别采用传统宫颈细胞涂片(535例)和新柏氏薄层细胞学检测系统(TCT526例)进行宫颈病变的早期筛查,对103例细胞学阳性或临床可疑的患者行阴道镜下活组织检查。结果TCT标本的不满意率(0.57%)明显低于传统宫颈细胞涂片(1.71%),明显提高了子宫颈癌及癌前病变的阳性诊断率,降低了对不典型鳞状细胞的诊断率。采用TCT配合阴道镜下镜检能及早发现癌前病变。结论宫颈细胞学筛查是子宫颈癌及癌前病变早期诊断的重要手段,TCT独特的取材与制片方法,更有利于宫颈阳性病变的检出;细胞学筛查异常或临床可疑的患者,应在阴道镜下多点活检;细胞学检查联合阴道镜对早期宫颈病变起到筛查作用。
Objective To analyze, compare and evaluate the approaches to testing cervical cancer and precancerous lesion so that the best approach to screening early cervical cancer can be confirmed. Methods Early screening of cervical cancer was conducted on 1,061 subjects respectively by traditional cervical cell smearing （n = 535 ） and Thinprep cytological test （TCT, n = 526）. Of the 1,061 subjects, 103 who were cytologically positive or clinically suspect underwent further biopsy under colposcope. Results The unsatisfactory rate was significantly lower in TCT samples （0.57%） than in traditional cervical cell smearing （ 1.71% ） , which showed that TCT could increase the positively diagnostic rate of cervical cancer and precancerous lesion. Furthermore, precancerous lesion was easy to be identified by TCT combined with colposcopy. Conclusion Cervical cytological screening acts as an important approach to the diagnosis of cervical cancer or precancerous lesion at early stage, and TCT is more propitious to the detection of positive cervical lesion. Those with abnormal cytological screening findings or with clinically suspicious manifestation should be further detected by biopsy at multiple spots under colposcope. Cytological test combined with colposcopy takes a vital role of screening early cervical lesion.
出处
《临床军医杂志》
CAS
2007年第4期568-570,共3页
Clinical Journal of Medical Officers
