摘要
目的:评价甲泼尼龙治疗Bell麻痹的效果。方法:将Bell麻痹96例随机分为泼尼松组(30例,泼尼松30 mg/d)、地塞米松组(32例,地塞米松10 mg/d)和甲泼尼龙组(34例,甲泼尼龙1 000 mg/d),各组均行维生素和理疗等基础治疗。采用H-B面神经功能分级量表、面部残疾指数量表(FD I)及面神经兴奋阈值和复合肌肉动作电位分别评定3组治疗前后神经功能的变化。结果:在临床、社会功能和电生理方面的总有效率,泼尼松组分别为70.00%、73.33%和63.33%;地塞米松组分别为68.75%、71.88%和62.50%;甲泼尼龙组分别为94.12%、97.06%和91.18%。甲泼尼龙在临床疗效、社会功能评价、电生理疗效方面均优于泼尼松组和地塞米松组,差异有显著性意义(P<0.05),而泼尼松组和地塞米松组间疗效无显著性差异(P>0.05)。结论:甲泼尼龙治疗Bell麻痹的效果明显优于泼尼松和地塞米松。
Objective：To evaluate therapeutic effect of Methylprednlsolone on Bell palsy, Methods：Ninety six patients enrolled in the study were randomly divided into 3 groups： Prednione group （ n = 30,30 mg daily） , Dexamethasine group （ n=32.10 mg daily） and Methylprednisolone group （ n = 34,1 000 mg daily）. All the patients were treated with same basic therapy of vitamine B and physiatries. House Braekmann Facial Nerve Grading System, Facial disability index,the threshold excitability and compound museule action potential of fiacial nerve were used to assess the nerve function before and after the treatment. Results：The total effective rate on clinlc,society function and eleetrophysiologieal evaluation were 70.00% ,73, 33% and 63.33% respectively in Prednione group,while 68.75% ,71.88% ,62.50% in Dexamethasine group and 94. 12% ,97.06% ,91.18% in Methylprednisolone group. The total effective rate on clinic,society function and electrophysiological evaluation in Methylprednisolone group were better than those in Prednione and Dexamethasine groups with significant differences（ P 〈 0. 05 ）. There were no significant differences between Prednione and Dexamethasine groups （P 〉0. 05 ）. Conclusion： Methylprednisolone is better than Prednione and Dexamethasine for Bell palsy.
出处
《临床误诊误治》
2007年第4期9-11,共3页
Clinical Misdiagnosis & Mistherapy
