摘要
目的观察鱼腥草注射液肺泡灌洗治疗神经外科重症监护室呼吸机相关性肺炎52例临床疗效。方法52例患者采用全身应用抗菌素结合床边纤维支气管镜龟腥草肺泡灌洗术治疗,观察患者术前术后的症状、体征、动脉血氧分压(PaO_2)、氧合指数,所有患者于灌洗前后48～72 h检查胸片。结果所有患者症状明显改善,灌洗治疗前后胸部X线片示病灶明显吸收,换气功能显著改善(P=0.000)。结论鱼腥草注射液经纤维支气管镜肺泡灌洗局部注药部位准确,浓度高,有效地清除脓痰和气道分泌物,抗感染疗效显著,减少了全身用药。
Objective To explore the clinical effects of bronchoalveolar lavage （BAL） with Yuxingcao injection in treating with 52 cases with ventilator-associated pneumonia （VAP） in neurosurgical intensive care unit （NSICU）. Methods BAL with Yuxingcao injection was performed by bedside fibrobronchoscopy in addition to systemic administration of antibiotics on the 52 patients with VAP. The preoperative and postoperative symptoms, signs, PaO2 and oxygenation index were measured and the chest radiography was performed for all patients 48-72 h before and after lavage. Results Symptoms of all patients were alleviated, chest X-ray pre- and post- lavage indicated that lesions were evidently absorbed and the patients＇ ventilatory function was obviously improved （P=0.000）. Conclusion The method was precise in localization and high in concentration by local injection; its anti-infectious effect was remarkable.
出处
《中华神经医学杂志》
CAS
CSCD
2007年第7期736-737,共2页
Chinese Journal of Neuromedicine
关键词
纤维支气管镜
肺泡灌洗
呼吸机相关性肺炎
Fibrobronchoscopy
Bronchoalveolar lavage
Ventilator-associated pneumonia
