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Caspase3在NS-398诱导宫颈癌Hela细胞凋亡中的作用 被引量:5

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摘要 环氧合酶2(COX-2)在多种恶性肿瘤中表达上调,能诱导肿瘤的发生、浸润和转移。非甾体抗炎药(NSAIDs)可降低消化系统恶性肿瘤的发生率和死亡率,其抗癌机制和抑制环氧合酶-2有关。环氧合酶2在慢性宫颈炎、不同宫颈癌FIGO分期、不同病理分级中的表达也存在递增趋势,
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2007年第12期711-713,共3页 Chinese Journal of Clinical Oncology
基金 湖北省教育厅科研基金资助(编号:D200511008)
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  • 1马向涛,王杉,杜如昱,叶颖江,崔志荣.Stat3反义寡核苷酸联合化疗调控结肠癌细胞增殖与凋亡的分子机制[J].中华实验外科杂志,2004,21(10):1212-1214. 被引量:25
  • 2Gaffney DK,Haslam D,Tsodikov A,et al.Epidermal growth factor receptor(EGFR) and vascular endothelial growth factor(VEGF) negatively affect overall survival in carcinoma of the cervix treated with radiotherapy[J].Int J Radiat Oncol Biol Phys,2003,56(4):922 被引量:1
  • 3Masferrer JL,Leahy KM,Koki AT,et al.Antiangeogenic and antitumor activities of cyclooxygenase-2 inhibitors[J].Cancer Res,2000,60(5):1306-1311. 被引量:1
  • 4Shao J,Lee SB,Guo H,et al.Prostaglandin E(2) stimulates the growth of colon cancer cells via induction of amphiregulin[J].Cancer Res,2003 ,63(17):5218-5223. 被引量:1
  • 5Rajnakova A, Moochhala S, Goh PM, et al. Expression of nitric oxide synthase, cyclooxygenase, and p53 in different stages of human gastric cancer[J]. Cancer Lett, 2001, 172(2):177-185. 被引量:1
  • 6Chang HC, Weng CF. Cydooxygenase-2 level and culture conditions influence NS398-induced apoptosis and caspase activationin lung cancer cells[J]. Oncol Rep, 2001, 8(6):1321-1325. 被引量:1
  • 7Minter HA, Eveson JE, Hundey S, et al. The Cydooxygenase-2-selective inhibitors NS398 inhibites proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis[J]. Clin Cancer Res, 2003, 9(5):1885-1897. 被引量:1
  • 8Harris RE, Alshafie GA, Abou-Issa HM, et al. Chemopreventive of breast cancer in rats by celecoxib, a cyclooxygense-2 inhibitor[J]. Cancer Res, 2000, 60(8):2101-2103. 被引量:1
  • 9Husain SS, Szabo IL, PaiR, et al. MAPK (ERK2) kinase-a key target fox NSAIDs-induced inhibition of gastric cancer cell proliferation and growth[J]. Life Sci, 2001, 69(25-26):3045-3054. 被引量:1
  • 10Hao XP, Bishop AE, Wallace M, et al. Early expression of cyclooxygenase-2 during sporadic colorectal carcinogenesis [J]. J Pathol, 1999, 187(3):295-301. 被引量:1

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