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左旋布比卡因硬膜外麻醉用于子宫切除术的临床观察

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摘要 目的探讨0.56%左旋布比卡因临床应用的可行性。方法选择A SA I-Ⅱ级择期行子宫切除术的病人60例,随机分为两组:Ⅰ组(n=30)用0.56%左旋布比卡因,Ⅱ组(n=30)用0.56%布比卡因,两组均先注入2%利多卡因为3-5m l试验剂量,针刺皮肤测试麻醉平面,密切观察5m in,确定无脊麻现象后,Ⅰ组注入0.56%左旋布比卡因10m l,Ⅱ组注入0.56%布比卡因10m l,术中连续监测心电图、心率、无创血压、血氧饱和度,观察感觉阻滞平面及范围,术中VA S评分,镇痛及肌松质量,运动阻滞时间,术期不良反应。结果Ⅰ组最高阻滞平面达T 6,Ⅱ组最高阻滞平面达T 7。感觉阻滞范围Ⅰ组平均为10个节段,Ⅱ组平均为8个节段;运动阻滞持续时间Ⅰ组长于Ⅱ组。Ⅰ组在术中探查和子宫切除时VA S评分低于Ⅱ组;Ⅰ组的肌松效果显示优于Ⅱ组;两组不良反应率相似。结论0.56%左旋布比卡因与等浓度的布比卡因用于子宫切除术的麻醉安全有效,临床效能差别,鉴于左旋布比卡因较短的麻醉诱导时间及较低的神经及心脏毒性,临床安全范围更大,具有一定的优越性。
出处 《西部医学》 2007年第4期628-629,共2页 Medical Journal of West China
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