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左旋布比卡因硬膜外阻滞在上腹部手术中的临床应用 被引量:2

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摘要 目的观察左旋布比卡因硬膜外麻醉用于上腹部手术的临床效能及不良反应,探讨临床应用的可行性,并与常用的局麻药布比卡因作对比分析。方法择期行胆囊手术的病人70例,随机分成两组:选择T8-9间隙行硬膜外穿刺置管;A组(36例)用0.56%左旋布比卡因,B组(34例)用0.56%布比卡因,两组分别注入左旋布比卡因或布比卡因3ml试验量,观察10min确定在硬膜外腔后A组注入0.56%左旋布比卡因10ml,B组注入0.56%布比卡因10ml,两组总量均为13ml;用针刺法测试麻醉起效时间、完全起效时间、这最高阻滞平面时间、麻醉阻滞平面及麻醉维持时间、麻醉质量、不良反应等。结果两组麻醉效果均较满意,总有效率两组无显著,巨差异(P〉0.05),起效时间、完全起效时间及维持时间无明显差异,这最高平面时间A组快于B组,两组比较有显著,巨差异(P〈0.05),术中HR、BP、SpO2无明显变化,两组均未发现严重局麻药不良反应。结论0.56%左旋布比卡因与等浓度的布比卡因用于上腹部手术的麻醉都是安全有效的,临床效能无明显差别,鉴于左旋布比卡因较短的麻醉诱导时间及较低的神经及心脏毒性,临床安全范围更大,具有一定的优越性。
机构地区 成都军区总医院
出处 《四川医学》 CAS 2006年第4期400-401,共2页 Sichuan Medical Journal
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  • 1李朝阳,袁星星,张敏,吴冬,敖杰.0.75%左旋布比卡因硬膜外麻醉用于子宫全切手术的观察[J].中国医师杂志,2006,8(4):568-569. 被引量:1
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