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急性心梗的冠状动脉病变和梗死部位与左室功能变化的研究 被引量:2

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摘要 目的:研究急性心梗(AMI)患者的冠状动脉病变和梗死部位与左室收缩、舒张功能变化的关系。方法:采用超声心动图测量30例冠状动脉造影正常、心功能正常者及101例AMI患者射血分数、左室短轴缩短率、舒张早期充盈峰值流速(E)、舒张晚期充盈峰值流速(A)、E/A比值。结果:与正常对照组比较,1支病变组舒张、收缩功能开始出现异常(P<0.05),2支病变组和3支病变组舒张功能、收缩功能下降更为明显(P<0.01)。不同梗死部位急性心梗的舒张功能均较正常对照组降低(P<0.05),ST段抬高的急性心梗收缩功能较正常对照组明显降低(P<0.01),而非ST段抬高心梗组与正常对照组比较则差异无显著性(P>0.05)。结论:AMI时冠状动脉病变影响心脏功能,并随冠状动脉病变程度加重而逐渐减退。由于梗死部位不同,左心收缩舒张功能亦随之变化,尤以广泛前壁,前壁和(或)前间壁梗死更为明显。
出处 《实用医学杂志》 CAS 2007年第11期1651-1652,共2页 The Journal of Practical Medicine
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