摘要
目的动态观察急性脑梗死不同发病时间血栓前体蛋白（TpP）含量的变化,探讨TpP测定对急性脑梗死早期诊断的临床价值。方法选择不同发病时间符合诊断标准的急性脑梗死患者58例,采用酶联免疫法测定血浆TpP含量,并与健康对照组比较。结果急性脑梗死组血浆TpP水平明显高于健康对照组（P〈0.01）,6小时开始升高,12-24小时达到高峰,尔后逐步下降,48小时后仍维持在较高水平。结论急性脑梗死TpP水平显著增高,脑梗死不同发病时间TpP水平不同,TpP可以作为急性脑梗死诊断的指标之一。
Objective To discuss the significance of the concentration change of plasma thrombus precursor protein （TpP） in acute cerebral infarction and investigate the diagnosis value of TpP. Methods 58 cases of acute cerebral infarction and 51 cases of healthy controls were selected. TpP was determined by enzyme linked inmunosorbent assay （ELISA）. Results The TpP level of acute cerebral infarction group was superior to that of the normal controls （P〈0.01）, The TpP concentration of routine group reach a peak in 12-24 hours. Conclusion TpP provides more referable values for the diagnosis and prognosis of acute cerebral infarction. It can be regarded as a diagnosis index of acute cerebral infarction.
出处
《中国现代医药杂志》
2007年第5期14-16,共3页
Modern Medicine Journal of China
关键词
脑梗死
血栓前体蛋白
Cerebral infarction Thrombus precursor protein
