摘要
目的评估上海市华阳、曹杨社区人群的血脂水平,描述血脂谱的人群流行特征。方法于1998年9月至2001年11月先后完成华阳、曹杨社区的5628例(20～95岁)调查对象代谢综合征的横断面调查。资料收集包括流行病学询问、体格检查和实验室血脂等指标的化验。以2000年全国人口构成为标准人口构成,计算两个社区成人血脂的标准化均数及标准化患病率。结果(1)标准化均数:华阳社区和曹杨社区成人TC,HDL-C,LDL-C和TG的标准化均数依次分别为5.01mmol/L和4.43 mmol/L,1.28 mmol/L和1.32 mmoL/L,3.37 mmol/L和2.99 mmol/L,1.97 mmol/L和1.60 mmol/L。(2)标准化患病率:按2005年6月16日上海血脂指南讨论会制定的血脂分层切点建议(2005)的划分标准,上海华阳、曹杨社区成人"血脂异常"的标准化患病率依次为52.9%和25.1%,"血脂边缘异常及异常"的标准化患病率分别为76.0%和56.2%。两社区"血脂异常"分类的标准化患病率从高到低依次均为:高 TG 血症、低 HDL-C 血症、高 LDL-C 血症和高 TC 血症。而华阳、曹杨"血脂合适范围"的标化百分构成从高到低均依次为 TC、TG、LDL-C 和 HDL-C,其中 HDL-C的百分构成远低于其他三项,仅为15.7%和16.1%。结论上海两社区成人"血脂异常"和"血脂边缘异常"的患病率均很高。人群血脂异常主要表现为高 TG 和低 HDL-C。
Objective To explore the adult lipid profile of Huayang community from 1998 to 2000 and Caoyang communities in 2001. Methods Representative serum samples of 5628 adults （ aged 20 - 95 years） were obtained in Huayang and Caoyang communities during 1998.9 and 2001.11. Standard epidemlology questionnaire, physical check-ups and serum lipids data were analyzed. Results After standardization to Chinese census statistics of 2000, the age-and sex-standardized means of total cholesterol, HDL-C, LDL-C and triglycerides of the two communities （ Huayang vs. Caoyang） were 5.01 mmol/L vs. 4. 43 mmol/L, 1.28 mmol/L vs. 1.32 mmol/L, 3.37 mmol/L vs. 2. 99 mmol/L, 1.97 mmol/L vs. 1.60 mmol/L respectively, and the age- and sex- standardized prevalence of dyslipidemia was 52. 9% vs. 25. 1%, and the prevalence for borderline dyslipidemia was 76.0% vs. 56. 2%, respectively. The decreasing order of dyslopidemia prevalence of the two communities was： elevated TG, decreased HDL-C, elevated LDL-C and TC. The standardized proportions of optimal HDL-C level were only 15.7% and 16. 1% in Huayang and Caoyang respectively which was much lower than these of TG, LDL and TC. Conclusions The standardized prevalence of adult dislipidemia and borderline dyslipidemia in the two communities were high. Dyslipidemia of the two communities was TG and decreased.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2007年第5期434-438,共5页
Chinese Journal of Cardiology
基金
上海市科委重大项目(04DE19501)
