摘要
在骨髓等组织内存在着一种非造血的干细胞——间充质干细胞，它可以在体内和体外被诱导，分化为骨细胞、软骨细胞、肌腱细胞、肌肉细胞和脂肪细胞等，具有多潜能的分化特性，而且比较易于提取和培养。随着肌腱组织工程理论和技术的不断发展，间充质干细胞的应用前景越来越广泛，并且发挥着重要的作用。就肌腱组织工程进行概述，对间充质干细胞的一般性质、来源以及将间充质干细胞作为种子细胞用于肌腱组织工程的进展等方面加以综述，并展望其发展前景。
There is a kind of nonhemopoietic stem cells in bone marrow mesenchymal stem cells. They can be induced and differentiated into osteocytes, chondrocytes, tenocytes, myocytes, adipocytes, et al both in vivo and in vitro. Therefore, they have the characteristic of differentiating into various kinds of tissues, called ＂muhipotential＂, and they are easily extracted and cultured. With the development in theory and technology of tendon tissue engineering, the application of mesenchymal stem cells becomes more and more widespread and important. This article will summarize the outline of tendon tissue engineering, the general characteristic and source of mesenchymal stem cells, as well as the research progress on mesenchymal stem cells used in tendon tissue engineering as seed cells. Furthermore, we will look into the future of this technique.
出处
《国际生物医学工程杂志》
CAS
2007年第2期112-115,共4页
International Journal of Biomedical Engineering
关键词
问充质干细胞
组织工程
种子细胞
肌腱
mesenchymal stem cells
tissue engineering
seed cells
tendon
