摘要
目的：观察扶正固本颗粒配合放射治疗中晚期食管癌的疗效。方法：将232例中晚期食管癌随机分为扶正固本颗粒加放疗组与单纯放疗组，两组均行常规分割放疗，1．8—2．0Gy／d，总量50—70Gy／5—8周。扶正固本颗粒加放疗组在行放疗的同时，给予扶正固本颗粒口服，15g／次，3次／日，50—55天为一疗程。结果：单纯放疗组1、3、5年生存率分别为41．4％、14．7％、7．6％，扶正固本颗粒加放疗组1、3、5年生存率分别为63．8％、29．3％、19．0％。1、3、5年生存率扶正固本颗粒加放疗组明显优于单纯放疗组（P〈0．05）。结论：扶正固本颗粒配合放疗可增加近期疗效与提高远期生存率，同时可减轻骨髓抑制等放射副反应。
AIM： To observe clinical effect of Fuzheng Guben Granules on mid-terminal esophagus cancer in combination with radiotherapy. METHODS ： 232 patients of mid-terminal esophagus cancer were divided randomly into radiotherapy group and Fuzheng Guben Granules associated with radiotherapy. 1.8 - 2.0 Gy per day, total 50 -70 Gy/5 -8 weeks. During the course of treatment with Fuzheng Guben Granules and radiotherapy, Fuzheng Guben Granules was administrated, 15 g once, 50 -55 days as a treatment course. RESULTS： The survival rates of the radiotherapy group in 1,3,5 years were 41.4%, 14.7% ,7.6%. The survival rates of Fuzheng Guben Granules associated with radiotherapy group were 63.8% ,29.3%, 19.03% in contrast, the survival rates of Fuzheng Guben Granules associated with radiotherapy group were obviously superior to the radiotherapy group in 1.3.5 years （P 〈 0.05 ）. CONCLUSION： Fuzheng Guben Granules associated with radiotheraphy can improve both immediate effect and long-term survival rate and reduce the side-reaction of marrow inhibition.
出处
《中成药》
CAS
CSCD
北大核心
2007年第4期484-486,共3页
Chinese Traditional Patent Medicine
关键词
扶正固本颗粒
食管肿瘤/放射疗法
预后
Fuzheng Guben Granules
esophogal cancer radiotherapy
prognosis
