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外周血干细胞移植物中残存肿瘤细胞的检测

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摘要 高剂量化疗联合自体外周血干细胞移植已经越来越多的应用于恶性肿瘤的治疗,干细胞移植物中肿瘤细胞的污染是导致疾病复发的主要原因之一,准确及时的检测出干细胞移植物中的肿瘤细胞具有重要的临床意义,其能更有利地掌握动员效果,有效地指导临床治疗,进一步提高造血干细胞移植的成功率,降低肿瘤的复发等。目前,PCR、免疫细胞化学和免疫磁珠等技术已经成为检测肿瘤患者外周血中微转移肿瘤细胞的主要方法,本文主要就这些方法做一综述.
作者 李娟 胡长路
出处 《临床输血与检验》 CAS 2007年第2期186-189,共4页 Journal of Clinical Transfusion and Laboratory Medicine
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