摘要
目的探讨早期乳腺癌保留皮肤的保乳手术的肿瘤学安全性。方法取50例行保乳手术的早期乳腺癌患者标本的肿瘤表面皮肤做连续切片并行病理检查,了解皮肤受累情况。结果50例早期乳腺癌患者接受保乳手术,皮肤切除范围(距肿瘤边缘):0.5～1.0cm21例,1.0～1.5cm25例,1.5～2.0cm4例,平均约1.2cm。1例Ⅱ期乳腺癌皮下组织见癌细胞浸润,皮肤受累率2%。皮肤受累与肿瘤表面皮肤改变相关(P<0.01),与肿瘤大小、病理类型、腋窝淋巴结转移无明显关系。结论早期乳腺癌皮肤受累率低,如无皮肤改变的临床表现,保留皮肤的保乳手术是安全的。
Objective To evaluate the oncologic risks of skin sparing breast conserving surgery for carcinoma of breast at early stage. Methods Serial sections of skin overlying the tumor were done for pathological examination in 50 cases of early stage breast cancer after skin sparing breast conserving operation. Results In 50 eases of breast conserving surgery, the extent of skin removal was 0.5-1.0cm in 21 eases, 1.0-1.5cm in 25 eases, and 1.5-2.0cm in 4cases. Skin involvement was found in one patient with stage Ⅱ breast cancer, and the rate of skin involvement was 2%. Skin involvement was closely related with the changes in skin overlying the tumor, but not with the tumor size, pathologic types or axillary lymph node metastasis. Conclusion The rate of skin involvement in early stage breast cancer is rare, therefore if there are no abnormal clinical manifestations in the skin, skin sparing breast conserving surgery is safe.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2007年第3期258-259,共2页
Medical Journal of Chinese People's Liberation Army
关键词
乳腺肿瘤
皮肤受累
保乳手术
breast neoplasm
skin involvement
breast conserving surgery
