摘要
目的检测乳腺癌中Fas抗原与C-erbB-2表达，探讨两者的相关性及与临床病理参数的关系．方法应用免疫组化SP法检测51例乳腺癌组织中Fas抗原与C-erbB-2表达，结果进行统计学分析．结果Fas抗原阳性率为56．9％，C-erbB-2阳性率为60．8％．结论Fas抗原与孔腺癌组织学分级、淋巴结转移呈负相关；C-erbB-2与组织学分级、淋巴结转移呈正相关；Fas抗原、C-erbB-2检测对判断乳腺癌预后、淋巴结转移有重要意义．
Objective To investigate the expression of Fas-Ag and C-erbB-2 in the tissue of breast cancer, we intended to find their interaction with clinic pathologic parameters. Methods To investigate the expression of Fas-Ag and C,-erbB-2 in the tissue of 51 patients with breast cancer by using SP method, then analyse and calculate the results. Results The expression of Fas-Ag in the tissue of breast cancer positive rate is 56.9 %, C-erbB-2 positive rate is 60.8 % . Conclusion The expression of Fas-Ag in the tissue of breast cancer is negative related to the hisological grades, lymph node metastasis, but C-erbB-2 is positive related to them. So investigation of the expression of Fas-Ag and C-erbB-2 in the tissue of breast cancer is important to prognosis and lymph node metastasis in the breast cancer.
出处
《北华大学学报（自然科学版）》
CAS
2007年第2期142-144,共3页
Journal of Beihua University（Natural Science）
