摘要
目的 探讨超敏C反应蛋白（hs—CRP）和幽门螺杆菌感染与冠心病之间的关系。方法 随机选取60例冠心病病人（冠心病组），包括急性心肌梗死、不稳定型心绞痛、陈旧性心肌梗死、稳定型心绞痛病人各15例，应用散射速率比浊法测定血清中hs—CRP浓度，ELISA法测定血清幽门螺杆菌IgG抗体，并与20例正常体检者（对照组）进行比较。结果 冠心病组hs—CRP浓度显著高于对照组（t’=8．14～18．59，P〈0．01），幽门螺杆菌IgG阳性率亦明显高于对照组（Х^2=4．310，P〈0．05）。结论 血中hs-CRP浓度升高和幽门螺杆菌感染与冠状动脉病变程度密切相关，对冠心病的病变程度有预测价值。
Objective To study the relationship between serum hypersensitive C-reactive protein （hs-CRP） level and helicobacter pylori （HP） infection and coronary heart disease. Methods Sixty patients with coronary heart disease were evenly divided into four groups at random, i.e. acute myocardial infarction, old myocardial infarction, stable angina, and unstable angina. Serum concentration of hs-CRP was determined by scatter velocity turbidimetry. HP-IgG were detected by ELISA. All the results were compared with that of 20 healthy subjects. Results The serum level of hs-CRP in the patients was significantly higher than that of the control group （t＇= 8. 14-18. 59, P〈0.01）. The positive rate of helicobacter pylori infection in the patients was significantly higher than that of the normal controls （Х^2 =4. 310,P〈0.05）. Conclusion The elevated serum level of hs-CRP and helicobacter pylori infection rate are closely associated with coronary heart disease, which can be used to predict the disease.
出处
《青岛大学医学院学报》
CAS
2007年第2期110-111,114,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
冠状动脉疾病
超敏C反应蛋白质
螺杆菌感染
coronary disease
hypersensitive C-reactive protein
helicobacter infections
