摘要
目的探讨黄芪注射液在治疗系统性红斑狼疮合并外周血白细胞减少症中对外周血白细胞总数及其分类计数的影响。方法选择外周血白细胞总数低于正常值的系统性红斑狼疮患者79例,随机分为常规治疗组(应用常量皮质类固醇和免疫抑制剂)和黄芪治疗组(在常规治疗的基础上加用黄芪注射液)。观察和比较两组患者在治疗前后外周血白细胞、中性粒细胞、淋巴细胞计数的变化。结果两组患者的外周血白细胞、中性粒细胞、淋巴细胞计数在治疗后均有不同程度的提高(P＜0．05),但两组患者治疗后外周血象的比较表明黄芪治疗组疗效显著优于常规治疗组(P＜0．05)。结论黄芪注射液在一定程度提高了应用皮质类固醇和免疫抑制剂治疗系统性红斑狼疮患者合并外周血白细胞减少症的疗效,可以作为提高系统性红斑狼疮疗效的重要治疗措施。
Objective To investigate the effects of radix astragali injection on the numbers and sorts of peripheral white blood cells during the treatment of SLE patients with leukopenia. Methods 79 SLE patients with leukopenia were randomly divided into the routine treatment group treated with the routine dose of corticosteroids plus immunosuppressants and radix astragali treated group treated with radix astragali injection plus routine treatment. The changes of leucocyte, neutrocyte and lymphocyte numbers in peripheral blood before and after treatment were observed and compared. Results After treatment, the numbers of leukocytes, neutrocytes and lymphocytes in peripheral blood increased in both groups （P 〈0.05）, and the effects was better in the radix astragali treated group （P 〈0.05）. Conclusion Radix astragali injection can enhance the curative effects of SLE patients with leukopenia and its effects are better than routine treatment.
出处
《兰州大学学报（医学版）》
CAS
2007年第1期76-78,共3页
Journal of Lanzhou University（Medical Sciences）
关键词
系统性红斑狼疮
黄芪注射液
外周血白细胞
白细胞减少症
systemic lupus erythematosus
radix astragali injection
peripheral blood leucocyte
leukoDenia
