摘要
目的为探讨不同程度窒息对新生儿胃泌素、胃动素及胃酸分泌的影响。方法对20例轻度窒息新生儿、25例重度窒息新生儿及20例正常新生儿于出生后1、3、7d检测血清胃泌素(GAS)、血浆胃动素(MTL)和胃液基础酸排量(BAO)。结果重度窒息组第1、3d的胃泌素、胃动素水平明显低于轻度窒息组,第7d两组间无显著差异。而第1d胃液基础酸排量则高于轻度窒息组。轻度窒息组第1、3、7d胃泌素、胃动素、BAO与正常对照组比较无显著差异。结论重度窒息新生儿血清胃泌素、血浆胃动素水平较轻度窒息新生儿明显降低,而胃液基础酸排量增高,这可能是导致新生儿喟养不耐受,易致消化道出血的原因。
Objective To study alteration of blood gastrin,motilin and the excretion of gastric acid in term newbom infants after asphyxia. Methods We checked concentration of blood gastrin,moti- lin and basal acid output （BAO） of 20 mild asphyxiated ,25 severe asphyxiated and 20 normal newborn infants in the first,third and seventh day of age. Results Serum gastrin was obviously lower in severe asphyxiated infants than mild one at the first and third day ,and so did serum motilin ,There were no deference between these two groups in the seventh day of age. BAO of severe asphyxiated infants at the first day of life was much higher than that of mild ones. There were no deference between mild asphyxiated and normal infants. Conclusion Lower gastrin,motilin and higher BAO put the severe asphyxiated infants at the risk of feeding intolerance and upper digestive tract hemorrhage.
出处
《医药论坛杂志》
2007年第1期37-38,共2页
Journal of Medical Forum
关键词
新生儿
窒息
胃泌素
胃动素
胃酸
Infant
Newborn
Asphyxia
Gastrin
Motilin
Gastric acid
