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亲体小肠移植术后并发症的内镜与病理监测

Endoscopic and pathological monitoring of postoperative complications following living-related small bowel transplantation
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摘要 目的探讨亲体小肠移植术后并发症的发生情况与防治。方法实施1例母亲为供体的小肠移植。通过内镜与病理检查对移植小肠并发症进行监测。结果移植手术过程顺利,受体生命体征稳定。术后第37天内镜和活检病理发现急性排斥反应,术后第65天活检病理发现巨细胞病毒感染。经激素冲击、OKT3抗排斥治疗,结合抗病毒治疗,病情得到控制,至发稿时已存活18个月。结论小肠移植患者容易发生急性排斥反应和感染等并发症,加强监护和采用内镜活检及病理检查可以及时发现隐匿的病情,控制病情,提高存活率。 Objective To investigate endoscopic monitoring and pathological evaluation of intestinal graft following living-related small bowel transplantation. Methods A case of small intestinal transplantation with mother donor was successfully performed on Nov 11, 2005. The complications of intestinal graft were regularly monitored with endoscope after transplantation. Results The operations on donor and recipient were performed successfully. Acute cellular rejection was diagnosed with pathological methods by endoscopic monitoring 37 days after transplantation. CMV infection was found in pathological examination 65 days after transplantation. The complications were successfully controlled by steroid impact and anti-virus therapy. Now the recipient has lived for 18 months after transplantation. Conclusion Acute cellular rejection and CMV infection is the common complications of small bowel transplantation. Post-operative monitoring with endoscope was helpful to find and control the complications.
出处 《中华消化内镜杂志》 2007年第1期41-44,共4页 Chinese Journal of Digestive Endoscopy
基金 广东省自然科学基金资助项目(05300755)
关键词 手术后并发症 小肠移植 结肠镜检查 活组织检查 Postoperation complication Small bowel transplantation Colonoscopy Biopsy
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