摘要
目的比较注射用奥扎格雷钠和川芎嗪治疗不稳定型心绞痛(UA)的疗效。方法将97例UA患者随机分为奥扎格雷钠治疗组(治疗1组)37例,川芎嗪治疗组(治疗2组)31例,对照组29例,3组患者均给予常规治疗。治疗1组加用奥扎格雷钠80 mg,加入5%葡萄糖注射液500 mL中,静脉滴注,qd。治疗2组每天加用川芎嗪100 mg,溶于5%葡萄糖注射液500 mL中,静脉滴注,qd。各组均治疗2周。2周后进行临床及实验室指标观察并进行比较。结果治疗1组和治疗2组的基本治愈率、显效率及总有效率明显高于对照组(P<0.05),治疗1组和治疗2组间差异无显著性(P>0.05)。结论奥扎格雷钠和川芎嗪治疗不稳定型心绞痛,具有显著的抗心肌缺血作用。
Objective To compare the therapeutic effects of sodium ozagrel and ligustrazine in the treatment of unstable angina pectoris（UA）, Methods Ninety-seven patients with UA were randomly divided into 3 groups： the sodium ozagrel group （ trial group 1 ,n = 37 ）, ligustrazine treated-group （ trial group 2, n = 31 ） and control group （ n = 29 ）, Patients of all 3 groups were subjected to conventional treatment for angina pectoris. Patients of the trial group 1 and 2 were given each additionally an injection of sodium ozagrel （ 80 mg ） and ligustrazine （ 100 mg ） added to 500 mL of 5% glucose solution administered by IV instillation q. d. , respectively. The course of treatment in all 3 groups lasted 2 weeks. Indexes of clinical manifestations and laboratory examinations in patients of the 3 groups were compared after the two weeks treatment. Results The basic cure rates, excellent effective rates and overall effective rates in patients of the 2 trial groups were obviously higher than those in patients of the control group （ P 〈 0.05 ）. However, the differences between patients of the trial group 1 and 2 were insignificant （P 〉 0. 05 ）. Conclusion Sodium ozagrel and ligustrazine were shown to have notable effects to relieve myocardial ischemia in the treatment of UA .
出处
《医药导报》
CAS
2007年第4期378-379,共2页
Herald of Medicine
关键词
奥扎格雷钠
川芎嗪
心绞痛
不稳定
Sodium ozagrel
Ligustrazine
Angina pectoris, unstable
