摘要
研究了2,6-二氨基-3,5-二硝基吡嗪-1-氧化物(LLM-105)的合成新方法.该方法是以2,6-二氯吡嗪和甲醇钠作为起始原料,经烷氧基化、硝化、胺化、N-氧化四步反应得到LLM-105,总收率为50%.用1HNMR,13CNMR,IR,MS和元素分析对LLM-105及其中间体结构进行了表征.
A new synthetic method of 2,6-diamino-3,5-dinitropyrazine-l-oxide （LLM-105） was discribed. LLM-105 was synthesized using 2,6-dichloropyrazine and sodium methylate as the starting materials in four steps including alkoxylation, nitration, amination and N-oxidation with total yield of 50%. The structures of intermediates and LLM-105 were determined by ^1H NMR, ^13C NMR, IR, MS spectra and elemental analysis.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2007年第1期112-115,共4页
Chinese Journal of Organic Chemistry
