摘要
目的 探讨绝经前后子宫内膜癌患者的临床病理特征、诊治及预后的相关因素。方法 将本院1992～2001年收治确诊为子宫内膜癌的120例患者分为绝经前后两组，绝经前组56例，绝经后组64例，分析两组患者的发病相关因素、临床病理特征、诊治及预后。结果 绝经前后两组患者子宫内膜样腺癌各占（85．7％、75％），两组Ⅰ期患者各占（64．3％、76．6％）。两组差异无统计学意义（P〉0．05）；两组比较，绝经前患者特殊病理类型少（分别为1．8％和12．5％），组织分级高，G1级（两组分别为67．9％和46．9％），深肌层浸润少（分别为13．7％和41．1％），宫颈受累多（分别为23．2％和9．4％）。5年生存率高（分别为96．4％和70．3％），上述各项差异均有统计学意义（P〈0．05）。另外，1期患者手术中是否行淋巴结清扫5年生存率差异无统计学意义。结论 绝经前子宫内膜癌患者的预后较好与其临床病理特征有关；Ⅰ期子宫内膜癌患者术中行淋巴结清扫不提高5年生存率；早期发现、诊断、治疗子宫内膜癌则预后较好。
Objective To investigate the clinical pathology, diagnosis and prognostic factors of endometfial carcinoma in premenopausal and postmenopausal women. Methods We retrospectively analyzed the data of 120 cases of admitted patients in our hospital from 1992 to 2001,56 cases were premenopausal women and 64 cases were postmenopausal women. Results There was no significant difference between premenopausal and postmenopausal women in the rate of endometrial adenocarcinoma （85.7% ＆75% ） and the stage one （64.3% ＆76.6% ）. The premenopausal group has lower special type （ 1.8% ＆ 12.5% ）, higher tumor grade （ G, were 67.9% ＆ 46.9% ）, less deep myoinertial invasion （13.7% ＆ 41.1% ）, higher cervical metastasis （23.2% ＆ 9.4% ）, higher five years survival rate （96.4% ＆ 70.3% ）, all of which have significant difference （P 〈 0.05）. Moreover, there was no obvious difference among the stage one patients by lymph resection in the five years survival rate. Conclusion The clinical and pathological type of endometrial carcinoma may lead to the better prognosis of premenopausal patients; Lymph resection in stage one patients can not improve the five years survival rate; Shortly, the earlier endometrial carcinoma is found, diagnosed and treated, the better prognosis will be.
出处
《中国医刊》
CAS
2007年第2期37-39,共3页
Chinese Journal of Medicine
关键词
绝经
子宫内膜癌
临床特征
预后
menopause
endometrial carcinoma
clinical character
prognosis
