摘要
目的探讨肝移植术后发生多器官功能不全综合征(mu ltip le organ dysfunction syndrom e,MODS)的危险因素。方法分析46例成人肝移植病例资料,分为MODS组和非MODS组,对合并的多种危险因素进行logistic回归分析。结果Ch ild分级、术中输液量、术中低血压时间、APACHEⅡ评分、机械通气时间、住ICU时间、血胆红素、血白细胞计数、血肌酐、术后肺部感染等在单因素分析中有统计学意义(P<0.05)。Logistic回归发现术后肺部感染、术中输液量是肝移植术后MODS的两个独立危险因素。结论术后积极防治肺部感染和减少肝移植手术中输液量是降低肝移植术后发生MODS的关键。
Objective To discuss the risk factors for Multiple Organ Dysfunction Syndrome after liver transplantation. Methods 46 adult patients who underwent liver transplantation were divided into two groups：MODS group and non-MODS group. A logistic regression analysis was carried out with variables that achieved a significant level of less than 0.05 in the univariate analysis. Results Child class, intraoperative total fluid perfusion, intraoperative hypotension time, APACHE Ⅱ scores, mechanical ventilatory time, intensive care time,total serum bilirubin,white blood cell count, serum creatinine, pulmonary infections after liver transplantation were of significance in the univariate a- nalysis （ P 〈 0.05 ）. A logistic regression analysis demonstrated that pulmonary infections after liver transplantation and intraoperative total fluid perfusion were two independent risk factors for MODS after liver transplantation. Conclusions Preventing pulmonary infections and decreasing intraoperative fluid perfusion are the keys to reduce the development of MODS after liver transplantation.
出处
《中国医刊》
CAS
2007年第2期31-33,共3页
Chinese Journal of Medicine
关键词
肝移植
多器官功能不全
预后
Liver transplantation
Multiple Organ Dysfunction Syndrome
Outcome
