摘要
研究桑白皮提取物(CM E)抗炎作用。结果表明,CM E显著抑制蛋清致炎1 h内大鼠足肿胀;对二甲苯所致小鼠耳肿胀、5-羟色胺所致小鼠足肿胀、组胺所致小鼠皮肤血管通透性增高具有显著对抗效果,延长4-氨基吡啶所致小鼠舔体潜伏期、减少舔体次数。因此,CM E具有抗炎、拮抗致炎介质组胺和5-羟色胺作用,提示其抗炎作用与抑制肥大细胞释放炎性介质有关。
The anti-inflammatory effects with the Cortex Mori extract （CME） was studied. It was found that CME could significantly inhibit the ear swelling induced by xylene in mice, and the paw edema caused by fresh egg white in rats. Moreover, CME significantly inhibited the histamine-induced cutaneous capillary permeability, the paw edema caused by 5-HT and licking response induced by 4-aminopyridine in mice. These results indicated that CME had the anti-inflammatory effects and suggested that the anti-inflammatory effects were related to the mast cell.
出处
《广西工学院学报》
CAS
2006年第4期23-26,共4页
Journal of Guangxi University of Technology
基金
广西工学院硕士基金项目
项目编号500413
关键词
桑白皮提取物
抗炎
炎症介质
肥大细胞
ortex Mori extract anti-inflammatory inflammatory mediators mast cell
