摘要
采用双盲随机对照法,观察一种新型的氯化十六烷基吡啶(Cetylpyridinium chloride,CPC)含漱剂对已形成的牙菌斑及慢性牙龈炎的疗效。实验过程中,120例慢性牙龈炎患者维持原有的口腔卫生习惯。结果显示,实验组的菌斑指数、牙龈指数及龈沟出血指数值在治疗后第7天与第14天时,均较服安慰剂组为低(P<0.01)。实验表明:CPC含漱剂能有效地控制菌斑,减轻龈炎的程度,改善患者的出血症状,且副作用极小。因而认为该种新型的漱口液在临床应用方面具有良好的前景。
The effect of a new CPC compound (cetylpyridinium chloride) mouthrinse on patients with formed plaque and chronic gingivitis was evaluated in a double blinded and randomized study. During the experiment, the patients kept their daily oral hygiene habit unchanged. The results showed that,indices of PLI,GI and SBI in the experimental group on days 7 and 14 were significantly lower than those of the placebo group ( P<0.01). The elimination rate of bleeding after the therapy was 75%. Since the results of the study showed this CPC compound mouthrinse had effects on controlling plaque and gingivitis with little side effect ,it might have a bright prospect in clinical use.
关键词
含漱剂
牙菌斑
牙龈炎
CPC
Mouthrinse
Anti-plaque agent
Dental plaque
Gingivitis
Cetylpyridinium chloride
