摘要
本文用善得定(sardostatin)治疗18例肝硬化食管静脉曲张破裂出血(EVB)。同期用垂体后叶素进行对比观察。结果显示:善得定治疗EVB止血总有效率为88.9%,垂体后叶素为55.6%;善得定平均止血时间为38分,垂体后叶素为74分;善得定治疗后平均失血量为325ml,垂体后叶素为568ml,两者相比疗效具有显著性差异(P<0.05)。善得定的副作用也明显少于垂体后叶素。因此。
This study aimed at comparing the effects of sandostatin(n=18)and pituitrin(n=18)on esophageal variceal bleeding(EVB). The results showed: The total effective hemostatic rate of sandostatin and pituitrin was 88.9% and 55.6% respectively. The mean hemostatic time of sandostatin and pitutrin was 38 minutes、74 minutes respectively. The mean amount of hemorrhage of sandostatin and pituitrin was 325ml、568ml respectively after administration. There was significant different effect between the sandostatin and pituitrin(P<0.05 ). It is suggested that sandostatin is superior to pituitrin in treatment of EVB with less adverse effect.