摘要
目的探讨帕罗西汀治疗老年期抑郁障碍的临床治疗和安全性。方法对入组的36例老年期抑郁障碍的患者使用帕罗西汀进行治疗,使用汉密尔顿抑郁量表(HAMD)与汉密尔顿焦虑量表(HAMA)及副反应量表(TESS)在治疗前,治疗后2、4、6、8周进行评定。结果治疗后2、4、6、8周(HAMD)评分及(HAMA)评分减分率显著(P<0.05)。TESS评分帕罗西汀副反应小,患者耐受较好。结论帕罗西汀对老年期抑郁障碍起效快,疗效显著尤其对焦虑、躯体化症状,副作用小,安全性高。
Objective To investigate the clinical therapy and safety of paroxetine in the treatment of senile depression. Methods Thirty six patients with senile depression were treated with paroxetine, and measured with Hamilton depressive scale （HAMD）, Hamilton anxiety scale （HAMA） and treatment emergent symptom scale （TESS） before treatment and 2,4, 6,8 weeks after treatment. Results The scores of HAMD and HAMA were significantly lower（ 0. 05） 2,4,6,8 weeks afrer treatment. The scores of TESS suggested paroxetine had fewer side effects and patients＇ drug tolerance was better. Conclusion Paroxetine is an effective and safe drug in the treatment of senile depression especially for anxiety and somatizatlon disorders, its side effects were fewer,
出处
《中国健康心理学杂志》
2007年第2期168-169,共2页
China Journal of Health Psychology
