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淀粉基口服结肠靶向给药控释载体 被引量:5

Starch-based Carrier for The Oral Colon-specific Drug Delivery System
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摘要 通过合理改性来调控淀粉的消化性能,使其具有不被上消化道消化、但能够被结肠微生物酵解的特性,则可用作口服结肠靶向药物控释载体。综述了淀粉的结构、消化特性、影响淀粉消化特性的因素及其在口服结肠靶向药物控释载体中的应用前景。 Starch can not be digested in the upper gastrointestinal but can be microbially decomposed in colon by suitable modifications which control starch digestibility, thus it can be used as carrier for oral colon-specific drug delivery system. This article provides a review of starch structure, digestibility and its influencing factors and the application outlook of starch-based carrier for oral colon-specific drug delivery system.
出处 《材料导报》 EI CAS CSCD 北大核心 2007年第2期116-119,共4页 Materials Reports
基金 国家自然科学基金(20376027) 广东省科技攻关项目(2005A10903002) 广州市科技成果推广项目(2005C13G0081)
关键词 淀粉 抗消化淀粉 口服结肠靶向 药物载体 starch, resistant starch, oral colon-specific, drug carrier
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参考文献27

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