摘要
目的研究盾叶薯蓣的水溶性化学成分,寻找活性物质。方法用系统溶剂提取,色谱法分离,光谱法鉴定结构,如:1H-NMR、13C-NMR、135DEPT、HMQC、HMBC、TOCSY。结果从盾叶薯蓣的水溶液中分离到一个薯蓣皂苷、一个苯苷类化合物、一个生物碱类化合物。薯蓣皂苷经测定分析,鉴定为26-O-(β-D-葡萄糖)-(25R)-furost-5-en-3β,26-diol-22-OMe-3-O-{α-L-鼠李糖-(1→4)-[β-D-葡萄糖-(1→3)-β-D-葡萄糖-(1→2)]-β-D-葡萄糖}。结论经文献检索为一新化合物,命名为盾叶薯蓣皂苷E(zingierenin E),另两个化合物在盾叶薯蓣中为首次报道。
Objective To study water-soluble constituents of Dioscorea zingiberensis in order to seek active components. Methods Various chromatographic techniques were used to isolate the constituents. Structures of compounds were elucidated by spectroscopic analyses of ^1H-NMR, ^13C-NMR, ^135DEPT, HMQC, HMBC, and TOCSY. Results One new steroidal saponin was isolated and identified as 26-O-（β-D-glucopyranosyl ）- （25R）-furost-5-en-313, 26-diol-22-OMe-3-O- {α-L-rhamnopyranosyl- （ 1 → 4 ）-[β-D-glueopyranosl- （ 1 → 3 ）-β-D-glucopyranosl- （ 1 → 2 ） ]-β-D-glueopyranoside }. Conclusion The compound is a novel compound named as zingierenin E. The other two compounds are reported for the first time from D. zingiberensis.
出处
《中草药》
CAS
CSCD
北大核心
2007年第1期6-8,共3页
Chinese Traditional and Herbal Drugs
基金
江苏省发改委资助
关键词
盾叶薯蓣
甾体皂苷
薯蓣皂苷E
Dioscorea zingiberensis C. H. Wright
steroidal saponin
zingierenin E
